AI + a16z

AI + a16z

by a16z

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.
103 episodes Updated 2mo ago Website ↗

Episodes 103 total

E104

How AI Is Rewriting the Rules of Cybersecurity | Truffle Security & Socket

Aug 7, 2026 · 23m

Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the big…

E103

Inside vLLM: The Engine Powering Open-Source AI

Aug 6, 2026 · 46m

Elena Burger and Matt Bornstein are joined by Simon Mo, co-founder and CEO of Inferact, the open-source inference engine powering many of today's most advanced…

E102

Building Self-Accelerating AI with Mirendil

Jun 24, 2026 · 40m

Matt Bornstein speaks with Mirendil cofounders Behnam Neyshabur and Harsh Mehta about their vision for building self-accelerating AI. After leading research eff…

E101

Ideogram’s Open-Weights Image Model and the Future of AI Design

Jun 15, 2026 · 42m

Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship be…

E100

Building Search for AI Agents with Exa CEO Will Bryk

Jun 4, 2026 · 49m

Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era. The conversation covers Exa’s origins, why tradition…

E99

AI Agents and the Fight for Customer Data

Jun 2, 2026 · 50m

Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI. The conversation covers Fivetr…

E98

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

May 19, 2026 · 29m

Recorded live at the a16z Fintech Connect conference in Deer Valley, Alex Rampell speaks with Ben Horowitz, cofounder and general partner at a16z, about how AI…

E97

AI Infrastructure, Distribution, and the Next Wave of Software

May 12, 2026 · 38m

Sophie Buonassisi speaks with Jennifer Li, general partner at a16z, about why infrastructure is becoming one of the most important areas in AI. They discuss how…

E96

From Vector Databases to Knowledge Engines: The Next Layer of AI

May 5, 2026 · 46m

Peter Levine speaks with Ash Ashutosh, CEO of Pinecone, about the launch of Nexus and the shift from vector databases to knowledge engines. As agents become the…

E95

Why We Need Continual Learning

Apr 28, 2026 · 18m

Elena Burger speaks with Malika Aubakirova, partner on the AI infrastructure team at a16z, about why today’s AI systems struggle to learn over time. They discus…

E94

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

Apr 21, 2026 · 59m

Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary use…

E93

Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon

Apr 8, 2026 · 47m

Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler i…

E92

How AI Is Reshaping IT Services from the Inside

Apr 1, 2026 · 34m

Joe Schmidt speaks with Peter Doyle, CEO of Treeline, about why the $100B managed service provider market is a decade behind modern technology and how Treeline…

E91

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Mar 24, 2026 · 52m

Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and…

E90

OpenClaw: Why the Internet Isn't Built for AI Agents

Mar 19, 2026 · 47m

Yoko Li, Guido Appenzeller, and Joel de la Garza discuss OpenClaw, the open source personal AI assistant that's forcing a rethink of how identity, permissions…

E89

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

Mar 17, 2026 · 47m

Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update thei…

E88

Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

Mar 10, 2026 · 1h 39m

Jack Neel speaks with Amjad Masad, CEO at Replit, about how AI is making it easier than ever to build and ship software without a technical background. They dis…

E87

Jack Altman & Martin Casado on the Future of VC

Mar 3, 2026 · 53m

Jack Altman sits down with Martin Casado, General Partner at a16z, to unpack the shifting dynamics of venture capital and why media matters more than ever. They…

E86

AI’s Capital Flywheel: Models, Money, and the Future of Power

Feb 24, 2026 · 57m

a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the histo…

E85

Durable Execution and the Infrastructure Powering AI Agents

Feb 19, 2026 · 1h 3m

Raghu Raghuram, Managing Partner at a16z, and Sarah Wang, General Partner at a16z, speak with Samar Abbas, CEO of Temporal, about how durable execution became t…