AI + a16z

AI + a16z

by a16z

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.
103 episodes Updated 2mo ago Website ↗

Episodes 103 total

E63

Tigris Data CEO on Building Your Own Datacenters

Nov 7, 2025 · 38m

In this episode, a16z General Partner Martin Casado sits down with Ovais Tariq, Cofounder and CEO of Tigris Data, to discuss why independent storage is so hard…

E62

Pylon: Reimagining B2B Customer Support

Oct 31, 2025 · 47m

Customer support platforms lacked adequate solutions for B2B companies - until Pylon entered the scene.We sat down with Pylon cofounders Marty Kausas, Advith Ch…

E61

Keycard: 2026 is the Year of Agents

Oct 22, 2025 · 32m

In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycar…

E60

The Trillion Dollar AI Software Development Stack

Oct 10, 2025 · 38m

AI coding has emerged as a major market for AI: one that’s already rewriting how software gets built.a16z Infra Partners Yoko Li and Guido Appenzeller break dow…

E59

Material Security CEO: How To Find Your Ideal Customer

Oct 6, 2025 · 34m

What if the hardest part of building a company isn’t the product, but knowing exactly who it’s for?In this episode, a16z General Partner Martin Casado sits down…

E58

When Deepfakes Steal $30M: The New Edge of Cybercrime

Sep 26, 2025 · 22m

AI is transforming both sides of the cybersecurity cat-and-mouse game. Attackers are using LLMs to scale impersonation, phishing, and even deepfake fraud—while…

E57

How AI Will Change Photography Forever

Sep 17, 2025 · 51m

What if you could retake your favorite memories years after they happened, fixing the lighting, catching the smile, or even opening your eyes?In this conversati…

E55

How OpenAI Built Its Coding Agent

Aug 29, 2025 · 1h 19m

OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the futur…

E54

Models, Modalities, and Memes: Creating Compelling AI Characters

Aug 14, 2025 · 47m

Models, Modalities, and Memes: Creating Compelling AI CharactersIn this episode of AI + a16z, Hedra founder and CEO Michael Lingelbach joins a16z partners Justi…

E53

Performance and Passion: Fal's Approach to AI Inference

Aug 1, 2025 · 40m

If you've been experimenting with image, video, and audio models, the chances are you've been both blown away by how good they're becoming, and also a little pe…

E52

How to Vibe Code Securely

Jul 25, 2025 · 26m

In this episode, a16z partner Joel de la Garza sits down with Socket founder and CEO Feross Aboukhadijeh to dive into the intersection of vibe coding and securi…

E51

AI Is Upending SaaS Pricing

Jul 18, 2025 · 42m

In this episode, a16z GP Martin Casado sits down with Metronome CEO Scott Woody to unpack how AI is fundamentally changing the value proposition of software—and…

E50

The AI Infrastructure Stack with Jennifer Li

Jul 11, 2025 · 45m

In this episode, which originally aired on the Complex Systems Podcast, a16z General Partner Jennifer Li discusses how AI is reshaping every layer of the softwa…

E49

AI's Unsung Hero: Data Labeling and Expert Evals

Jun 27, 2025 · 46m

Labelbox CEO Manu Sharma joins a16z Infra partner Matt Bornstein to explore the evolution of data labeling and evaluation in AI — from early supervised learning…

E48

AI, Data Engineering, and the Modern Data Stack

Jun 20, 2025 · 35m

In this episode of AI + a16z, dbt Labs founder and CEO Tristan Handy sits down with a16z's Jennifer Li and Matt Bornstein to explore the next chapter of data en…

E47

Enabling Agents and Battling Bots on an AI-Centric Web

Jun 13, 2025 · 26m

Arcjet CEO David Mytton sits down with a16z partner Joel de la Garza to discuss the increasing complexity of managing who can access websites, and other web app…

E46

Giving New Life to Unstructured Data with LLMs and Agents

Jun 6, 2025 · 35m

Instabase founder and CEO Anant Bhardwaj joins a16z Infra partner Guido Appenzeller to discuss the revolutionary impact of LLMs on analyzing unstructured data a…

E45

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

May 30, 2025 · 1h 41m

LMArena cofounders Anastasios N. Angelopoulos, Wei-Lin Chiang, and Ion Stoica sit down with a16z general partner Anjney Midha to talk about the future of AI eva…

E44

Building AI Systems You Can Trust

May 23, 2025 · 47m

In this episode of AI + a16z, Distributional cofounder and CEO Scott Clark, and a16z partner Matt Bornstein, explore why building trust in AI systems matters mo…

E43

Who's Coding Now? AI and the Future of Software Development

May 16, 2025 · 44m

In this episode of the a16z AI podcast, a16z Infra partners Guido Appenzeller, Matt Bornstein, and Yoko Li explore how generative AI is reshaping software devel…