Latest episodes 5,554 total
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Saturday, October 17
Friday, October 16
The Most Important AI News This Week Is Getting Overlooked
The most consequential AI announcements this week might be the ones getting the least attention. NLW explores what Microsoft’s MAI Base 2 and Meta’s Muse Spark…
Cars and Houses
Happy Friday.We’re live on YouTube and 𝕏.The current thing in tech and business is the launches of Tesla’s Roadster and Porsche’s Miss…
Is This the Cheapest Way to Use AI in 2026? (65+ Models Tested) | Iskander Malikov, Trioma
What if you didn't have to choose between ChatGPT, Claude, and Gemini, and instead, the platform chose for you? That's the core idea behind Trioma, a vertically…
Why No One Can Look Away From Elizabeth Holmes
This week, there’s a new blockbuster Elizabeth Holmes documentary out, and we’ve assembled an expert panel to discuss the movie and what Holmes means to the tec…
Gemini 4 & Meta's Muse Wonder Are Good. Not Great.
AI news this week: Google's Gemini 4 Argon and Meta's Muse Wonder are finally here, plus Xbox Labs, Epic's big AI pivot and an AI agent vs. Delta customer servi…
Modernizing Enterprise GRC for Continuous Assurance - with Craig Unger of Hyperproof
Shifting regulations and siloed risk and compliance functions are forcing enterprise leaders to rethink audit-driven compliance. In this episode, Craig Unger, C…
Thursday, October 15
How the Latest AI Leap Is Disrupting Business Models
AI’s latest capability jump is forcing companies to rethink their business models. From Adobe clones to one-person game studios, NLW explores what’s changing, w…
Recapping Anthropic Investor Day
Happy Thursday.We’re live on YouTube and 𝕏.The current thing in tech and business is Anthropic’s numbers from Investor Day.Today’s Lin…
The Changing Physics of Cybersecurity and Drug Development with OpenAI President Greg Brockman
Technology has always been the fundamental driver of improvement for human quality of life. And with the recent rollout of advanced frontier models, like OpenAI…
The Real‑World Conditions That Shape Industrial AI - with Jeff Witt of GE Vernova
A recommendation that's right 80% of the time sounds fine, until it's steering machinery next to a person. On the factory floor, that margin is the difference b…
Elizabeth Holmes' Husband Billy Evans: The Trial, Prison & Nathan Fielder's Documentary
(0:00) Billy Evans joins Friedberg (3:38) How they met, Elizabeth the person vs the headlines, indictment (11:02) Life on trial, having a child, where she went…
Wednesday, October 14
Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio
A few years ago I stumbled upon Leash Bio’s Substack, and was hooked. Be it their Kaggle competition that showed that no, we really haven’t solved protein-ligan…
What Gemini 4 Argon Is Actually Good For
Google’s newest model is here, with mixed coding reviews, impressive visual demos, and a surprising strength in writing. NLW explores where Gemini 4 Argon could…
Listening Devices
Happy Wednesday.We’re live on YouTube and 𝕏.The current thing in tech and business is OpenAI revealing that an employee planted a sophisticated re…
Tuesday, October 13
Dyna-2: General Purpose Physical Agents with Hour-Long Autonomy — Jason Ma, Dyna Robotics
Watch along AIE NYC and join us at AIE CODE in SF next month!This episode includes a live demo of the Taku robot that is best enjoyed on YouTube.Last month, Dyn…
Why Muse Wonder Is Dividing AI Users
Meta’s Muse Wonder is earning both glowing praise and sharp criticism. NLW explores the gap between benchmarks and real-world results, the crucial differences b…
The Social Reckoning Asks No Hard Questions
Happy Tuesday.We’re live on YouTube and 𝕏.The current thing in tech and business is Mark Zuckerberg saying Meta has reached AI ‘frontierR…
AI Content Governance Inside a Regulated Bank - with Stefan Zima of Raiffeisen Bank International AG
Financial institutions are moving fast on generative AI without a clear answer for who owns, and who is liable for, the content it produces and consumes. In thi…
October 12
Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him
(0:00) Martin Shkreli joins the Besties! (0:55) Why quantum computing is a one-trick business and why he's betting against it (7:42) The drugs big pharma sells…
How to Go from AI Power User to AI Leader
As AI becomes central to work, a new leadership opportunity is emerging for those who can help others use it effectively. In this Operator's Cut, NLW and Nu…
October 11
October 10
What Most People Get Wrong About Evolution | Akarsh Kumar
A lot of people in AI treat evolution as a dumb fallback, basically random search for when you can't take a gradient. Akarsh Kumar thinks that is wrong. Sel…
Is Claude Conscious? Pope Rejects, Model Welfare Movement, OpenAI's Math Backlash, France Riots
(0:00) Bestie intros! (2:53) Anthropic believes Claude might be conscious: a new religion? Lobbying the Pope, alignment risks, model welfare (38:28) OpenAI's ma…
Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub
From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding, Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido are rethinking what…
October 9
When AI Solves Your Life’s Work
OpenAI’s latest mathematical results are forcing researchers to confront what happens when AI can tackle problems that once defined entire careers. With hundred…
Beam: The Great American Open Model with ReflectionAI Co-Founder and CEO Misha Laskin
Is the future of frontier AI open or closed? ReflectionAI co-founder and CEO Misha Laskin joins Sarah Guo and Elad Gil to discuss the launch of Beam, the compan…
Chat GPT's Creator Explains The Shocking Truth About How AI Understands the World | Ilya Sutskever
Craig Smith sits down with Ilya Sutskever - Co-Founder and Chief Scientist at Safe Superintelligence Inc. & former chief scientist at OpenAI and one of the prim…
Anthropic’s Quest to Give A.I. Morals
This week, Max Read talks to the Times religion correspondent Elizabeth Dias, the tech reporter Erin Griffith and the opinion writer David Wallace-Wells about A…