Latest episodes 5,554 total
October 1
Si Sheppard – How did a few hundred Spanish soldiers topple two empires?
New episode with military historian Si Sheppard.The conquests of the Aztec and Inca empires might be the most shocking events in human history.Hernan Cortés and…
What’s Next for ‘Hard Fork’?
For the next few months on “Hard Fork,” join the guest host Max Read and an array of Times reporters and experts as we zoom out, catch up and try to understand…
September 30
Why Dwarkesh is Wrong about Computer Use + How OpenAI shipped its Jev competitor in 1 Week
Three months ago Dwarkesh, who has been posting incredible blogs and episodes about RL, posted a framing question for his video essay on RLVR which upset a lot…
Jake Paul & The Chainsmokers: Turning Fame into Funds, Jake Enters Politics? & Venture Bubble Signs
(0:00) Jake Paul joins the Chamath! (6:41) Turning an audience into businesses, the boxing playbook & coming for the UFC (11:54) Attention as capital, investing…
The Most Important New AI Tools from OpenAI DevDay
OpenAI unveiled more than 20 launches at Dev Day, from always-on Dots agents and the shared workspace Space to cheaper models and new ways to use your ChatGPT s…
Dollars per Watt
Happy Wednesday.We’re live on YouTube and 𝕏.The current thing in tech and business is everything OpenAI announced at DevDay.Today’s LineupNV…
Why Current AI Cannot Be Conscious | Dr. Christof Koch
One in four patients currently being considered for life support withdrawal may actually be fully conscious, they just can't signal it. That single finding, fro…
Who Checks a Proof No Human Can Read? — Leo de Moura
Leonardo de Moura created Lean and co-created Z3. ---This episode is sponsored by Parallel.Parallel, where agents find answers: web search, extraction and deep…
September 29
🔴 Sam Altman is LIVE on TBPN right now
We’re live with OpenAI CEO Sam Altman right now from OpenAI DevDay.Tune in here.Special thanks to our sponsors: Ramp, Codex, Shopify, CrowdStrike, MongoDB…
How to Build Team Agents
Nufar Gaspar joins this AIDB Operator’s Cut to explore how to build AI agents that work for an entire team. The conversation focuses on moving from individual A…
Where AI Should Actually Earn Its Keep in Biopharma - with Mukhtar Ahmed of Greenstone Biosciences
In biopharma R&D, AI investment has overwhelmingly targeted generating more drug candidates, even though the industry has rarely lacked for compounds worth purs…
Claude Code’s Next Era — Thariq Shihipar, Anthropic
We are excited to have Anthropic share their latest AI x Finance work at AI Engineer New York, coming up in 2 weeks!In case you’ve been under a rock, here’s a n…
September 28
Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential
(0:00) Daniel Ek joins the Besties! (1:14) Starting Spotify: Beating piracy and betting his own money on the record labels (6:10) Neko Health: The Spotify playb…
From SNL Straight to the White House
Happy Monday.We’re live on YouTube and 𝕏.The current thing in tech and business is MongoDB CEO CJ Desai joining Meta, tanking the MongoDB stock.To…
The Real Risks of AI Agents
AI agents don’t have to pose an existential threat to cause serious disruption. NLW examines recent OpenAI security incidents, the limits of agent permissions…
September 27
September 26
When AI Research Starts Moving Faster Than Human Research - Zhengyao Jiang
Weco let an AI coding agent rewrite the harness around another agent for eight days: its code, prompts and tools, while the underlying language model stayed fix…
Anthropic IPO at Risk, Meta's Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails
(0:00) Bestie Intros: Favorite All-In Summit moments (3:54) Reacting to AI chaos: Liability, competition, and rebranding frontier "labs" (20:03) Open Source per…
September 25
OpenRouter: from Seed to Stripe — with OpenRouter’s Alex Atallah & AMP’s Anjney Midha
From the earliest days of open-weight models to becoming the neutral routing layer for more than 10 million developers, OpenRouter is one of the clearest bets t…
How People Are Actually Using Jev
Jev is moving beyond viral demos into practical work, from analyzing ad campaigns and searching archives to prioritizing inboxes and checking AI writing. NLW br…
Four Tech Debates
Happy Friday.We’re live on YouTube and 𝕏.The current thing in tech and business is the stacked guest list at the Trump-Xi White House dinner.Today…
The Ezra Klein Show: Jensen Huang Thinks A.I. Alarmism Has Gone Too Far
In this episode, Ezra travels to Nvidia’s headquarters in Santa Clara, Calif., for a wide-ranging conversation with the chief executive Jensen Huang about the f…
Runway’s WorldPrompt and the Engineering of Real-Time Worlds
Earlier this month, world model company Runway introduced GWM Worlds 2, a research preview that “turns high-fidelity video and audio generation into real-time i…
September 24
AI Agents Are Moving Into the Real World
Meta is bringing Muse to smart glasses and a new wearable, while GrokBot is turning Teslas into voice-controlled personal assistants. As skeptics question wheth…
Everything Announced at Meta Connect
Happy Thursday.We’re live on YouTube and 𝕏.The current thing in tech and business is everything announced at Meta Connect.Today’s LineupEncl…
The Technology for Fully Autonomous Attack Is Already Here | Alex Liannyi, NORDA Dynamics
The AI systems guiding Ukrainian combat drones aren't running on expensive Nvidia chips. They're running on a Raspberry Pi Zero - a $15 hobby computer - and tha…
Opus 5.5 is our favorite AI model (so far).
AI news this week: Claude Opus 5.5 is INSANE and we love it. Faster, cheaper, better. So much for the AI slowdown. Oh and OpenAI's new thing is good too. On tod…
Re-Founding Incumbents for the AI Era with Sequence Holdings Co-Founder and CEO Michael Lee
Can AI transform legacy incumbents rather than replacing them? Sequence Holdings co-founder and CEO Michael Lee joins Sarah Guo to discuss how holding company s…
Modernizing Finance Data for Faster and More Reliable Operations - with Ciprian Porutiu of Marsh
Finance teams face immense pressure to operate faster, but rushing to automate over fragmented systems only compounds errors downstream. Ciprian Porutiu, SVP of…
#257 - GPT 6 Astra, AI Extinction, Security Incidents
Our 257th episode with a summary and discussion of last week's big AI news!Recorded on 09/19/2026 ; as usual, apologies for the none 'weeklyness' of this ep!Hos…