Latest episodes 5,554 total
September 17
Transforming Cardiovascular Care — How AI-Driven Insights Unlock Value for Hospitals and Clinics - with Jim Hartman of Cleerly
Hospitals and clinics continue to face a central challenge: extensive cardiac testing still fails to deliver clear, consistent diagnostic answers, slowing decis…
Brad Gerstner: No AI Bubble, Semis Eat the Nasdaq & AI's Take Off Problem
(0:00) Welcome Brad Gerstner! (1:01) Trump Accounts, Every Child a Capitalist & The CAC Scan (5:07) Can AI revenue pay for the CapEx? (8:53) The Build Out Issue…
#502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
Andrew Scull is a historian of psychiatry. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep502-sc See below for timestamps…
September 16
Why a New Class of AI “Judgment Models” Could Have Big Business Implications
A new AI model called Jev is built to make fast, inexpensive judgments rather than generate text. NLW explores how this approach could reshape business automati…
Underwriting Superintelligence: Backing Agents you can Sue — Rune Kvist, AIUC
AIUC first got our attention with the NFDG backing, and have just announced a $40M series A today, with the most impressive industry advisor list we may have ev…
Third Party Evaluators
Happy Wednesday.We’re live on YouTube and 𝕏.The current thing in tech and business is Zuck’s response to the AI slowdown debate.Today’…
September 15
JD Vance on AI, Entitlement Fraud, Iran War, Israel, H-1B Abuse & the Midterms
(0:00) VP JD Vance joins The Besties! (1:40) Assessing the Trump Admin so far: Border control, re-industrialization, inflation, Iran, government debt, anti-frau…
Trump Rails Against AI Slowdown "Hoax"
Trump is pushing back against calls for an AI slowdown, dismissing warnings of AI catastrophe as a hoax. NLW examines Jensen Huang’s response, Obama’s support f…
High Interest Rate Phenomenon
Happy Tuesday.We’re live on YouTube and 𝕏.The current thing in tech and business is ten-year treasury yields hit 5% for first time since 2023.Toda…
Satya Nadella on the AI Doomer Slowdown, Microsoft's Master Plan & Who Wins AI
(0:00) Satya Nadella joins The Besties! (0:55) Dario's blog, "pacing the frontier," common sense AI safety (6:28) The failure of AI CEO messaging, monitoring ag…
How Physical AI Learns Across Language, Video and Action — Ming-Yu Liu
The car making a left turn at the start of this episode was never filmed. Cosmos 3 generated it. Ming-Yu Liu, who leads the Cosmos research at NVIDIA, explains…
Closing the Gap Between Commercial Plans and What Happens on the Shelf - with Stephanie Lilley of Reckitt
For consumer goods companies, the gap between the commercial plan agreed at head office and what gets executed on the shelf is one of the costliest disconnects…
Elon Musk & Gwynne Shotwell on AI Risks and Peer Review, Starship, Terafab, SpaceX/Tesla Merger
(0:00) SpaceX's Gwynne Shotwell joins The Besties! (1:45) Gwynne's SpaceX story, selling rockets, and working for Elon (6:45) Running modern day SpaceX: AI, Sta…
September 14
Even Other AI Labs Are Rallying Around Anthropic’s Slowdown Proposal
Leaders at rival AI labs are publicly backing Anthropic’s proposal for an AI slowdown, marking a significant shift in the debate over how the technology should…
Jensen Huang: The Doomer Hoax, Superintelligence Is Here, and The Future of AI (ft. President Trump)
(0:00) Jensen Huang joins The Besties! (1:39) Thoughts on Dario's blog, Frontier Labs calling to slow down AI, and Doomer psychology (9:58) Sensible AI regulati…
Speech Recognition Is Not a Solved Problem — Pavan Kumar Reddy
Pavan Kumar Reddy leads audio research at Mistral AI. He joins Tim Scarfe for a deep technical tour of Voxtral — and explains why the frontier of deployed voice…
What Just Happened With the “Pacing AI” Debate
Happy Monday.We’re live on YouTube and 𝕏.The current thing in tech and business is Dario’s blog “We Must Pace the Frontier.”Toda…
Humanity’s Last Invention — Richard Socher of Recursive
At 1:09:00 we talk about the rise of AI x Finance, and AIE NYC is one month away - our hotel block is 97% sold out, get tix & travel ASAP - we will announce spe…
The Hidden Algorithm That Decides Which Software AI Will Recommend | Tim Sanders, G2
Most companies investing in AI visibility are optimizing for the wrong thing. Being cited by an AI response and being recommended by an AI response are complete…
Why Traditional Training Can't Keep Technical Teams Current - with Nicola Lyons of Andela
Traditional, event-based training can't keep pace with technical skills that now shift every six to twelve months. In this episode, Nicola Lyons, Senior Direc…
September 13
September 11
AI Kills Everybody or Doomer Psyop? OpenAI's Math Breakthrough, Nike's $200B Collapse
(0:00) Bestie intros! (0:35) AI Doomsday: Valid concern or Doomer psyop? (33:40) Steelmanning AI Doomsday scenarios and the impact on Anthropic's IPO (58:45) Op…
How Replication Could Teach Machines What Good Science Looks Like — Edward Hughes
Can a machine learn the judgement that separates a plausible-looking result from a faithful experiment? Edward Hughes, Chief Scientist and co-founder of Inheren…
What to Use the Latest AI Tools For
GPT‑Live 1 opens up a much wider range of real-time voice and vision applications, from customer service and sales to education, healthcare, and hands-free work…
What Are the AI Doomers Actually Proposing?
Happy Friday.We’re live on YouTube and 𝕏.The current thing in tech and business is the ethics debate around the scanning the full brain of a fruit…
AI researchers debate how close we are to recursive self-improvement
New episode with John Schulman, Beren Millidge and Charlie O’Neill. I got together with some of the most insightful AI researchers I know who are at the openish…
The Ezra Klein Show: The A.I. Revolt Is Here
The “Hard Fork” team is away this week. But while we’re away, we’re bringing you a recent episode of “The Ezra Klein Show.”In this episode, Ezra talks with the…
September 10
Anthropic Researcher Says AI Has Over a 10% Chance of Killing All Humans
An Anthropic researcher puts the chance of AI killing all humans at more than 10% within the next decade. Why is this warning breaking through now? NLW examines…
YC Doom-o Day
Happy Thursday.We’re live on YouTube and 𝕏.The current thing in tech and business is AI researcher Andrew Tulloch, who left Thinking Machines to j…
The Reason 30 Years of Cybersecurity Has Failed - and What Actually Fixes It | Trent Telford, Qanapi
Every major data breach in the last 30 years shares the same root cause: the data inside the wall was never protected, only the wall. And AI frontier models are…