No Priors: Artificial Intelligence | Technology | Startups
Episodes 183 total
Why Platforms Win and Point Solutions Fail with Rippling CEO Parker Conrad
As a three-time founder, Parker Conrad has one piece of advice for aspiring entrepreneurs—don’t do it. The Rippling co-founder and CEO joins Sarah Guo to talk a…
Chai-2: The AI Model Accelerating Drug Discovery with Chai Discovery Co-Founders Jack Dent and Joshua Meier
AI has already fueled breakthroughs in biotechnology—but now, further advances in AI are poised to fuel pharmaceutical discoveries as well. Sarah Guo sits down…
Meet AlphaEvolve: The Autonomous Agent That Discovers Algorithms Better Than Humans With Google DeepMind’s Pushmeet Kohli and Matej Balog
Much of the scientific process involves searching. But rather than continue to rely on the luck of discovery, Google DeepMind has engineered a more efficient AI…
The Operating System for Self Driving Cars (and Tanks, and Trucks...) With Qasar Younis and Peter Ludwig of Applied Intuition
When will fully autonomous vehicles see widespread adoption? According to Applied Intuition, that future is closer than you may think. Applied Intuition’s CEO…
Will we have Superintelligence by 2028? With Anthropic’s Ben Mann
What happens when you give AI researchers unlimited compute and tell them to compete for the highest usage rates? Ben Mann, Co-Founder, from Anthropic sits down…
Teaching AI to Understand the Physical World, with Dr. Fei-Fei Li of World Labs
In this episode of No Priors, Sarah and Elad are joined by Dr. Fei-Fei Li, AI pioneer, co-director of Stanford’s Human-Centered AI Institute, and founder of Wor…
AI Consolidation, Biotech Opportunities, and World Models with Sarah and Elad
In this episode of No Priors, Sarah and Elad unpack the current state of the AI market - whether it’s consolidating, what’s enabling or blocking key mergers, an…
AI is Making Enterprise Search Relevant, with Arvind Jain of Glean
Arvind Jain joins Sarah and Elad on this episode of No Priors. Arvind is the founder and CEO of Glean, an AI-powered enterprise search platform. He previously c…
Gaming as the Future of Education with Duolingo CEO Luis von Ahn
On this episode of No Priors, Sarah talks to Luis von Ahn, founder and CEO of Duolingo, the world’s most popular education app with over 116 million monthly use…
O3 and the Next Leap in Reasoning with OpenAI’s Eric Mitchell and Brandon McKinzie
This week on No Priors, Elad and Sarah sit down with Eric Mitchell and Brandon McKinzie, two of the minds behind OpenAI’s O3 model. They discuss what makes O3 u…
Inside Deep Research with Isa Fulford: Building the Future of AI Agents
On this episode of No Priors, Sarah sits down with Isa Fulford, one of the masterminds behind deep research. They unpack how the initiative began, the role of h…
Predicting the Earth with Josh Goldman: How KoBold Uses AI to Find Critical Minerals
This week on No Priors, Sarah and Elad are joined by Josh Goldman, cofounder and president of KoBold Metals. KoBold is using AI to transform how we discover cri…
From Job Displacement to AI Trainers, Brendan Foody on Work in the AI Age
On this episode of No Priors, Sarah and Elad sit down with Brendan Foody, CEO and cofounder of Mercor, to discuss the company’s rapid growth and their vision fo…
Public Markets, Image Gen, and Specialized Models, with Sarah and Elad
In this episode of No Priors, Sarah and Elad examine the current state of AI. They break down the recent dip in public markets, how tariffs could impact the tec…
Conversations Are the Source of Truth in Healthcare with Abridge CEO Shiv Rao
In this episode of No Priors, Elad and Sarah chat with Shiv Rao, MD, founder and CEO of Abridge. They dive into how Abridge is reshaping healthcare by creating…
The Robotics Revolution, with Physical Intelligence’s Cofounder Chelsea Finn
This week on No Priors, Elad speaks with Chelsea Finn, cofounder of Physical Intelligence and currently Associate Professor at Stanford, leading the Intelligenc…
Copilot, Agent Mode, and the New World of Dev Tools with GitHub’s CEO Thomas Dohmke
This week on No Priors, Sarah and Elad talk with GitHub CEO Thomas Dohmke about the rise of AI-powered software development and the success of Copilot. They dis…
National Security Strategy and AI Evals on the Eve of Superintelligence with Dan Hendrycks
This week on No Priors, Sarah is joined by Dan Hendrycks, director of the Center of AI Safety. Dan serves as an advisor to xAI and Scale AI. He is a longtime AI…
Building the Platform for Scientific Breakthrough, with Noubar Afeyan of Moderna and Flagship Pioneering
This week on No Priors, Sarah sits down with Noubar Afeyan, Co-founder and CEO of Flagship Pioneering, the biotech firm behind groundbreaking companies like Mod…
Virtual Cell Models, Tahoe-100 and Data for AI-in-Bio with Vevo Therapeutics and the Arc Institute
On this week’s episode of No Priors, Sarah Guo is joined by leading members of the teams at Vevo Therapeutics and the Arc Institute – Nima Alidoust, CEO/Co-Foun…