Latent Space: The AI Engineer Podcast
Episodes 235 total
🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
Bet on informationIf test loss flatlines after 1.5B parameters while training loss continues to drop as you scale, that tells you that your model is limited by…
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
Imagine a dark warehouse. Racks and racks of devices with wires, tubes, and electronics sticking out. The next AI data center? No. This is Lila Sciences‘ dream…
Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO
We’ve been running a bit of an Agent Cloud series surveying all the top inference/compute/cloud providers, from Databricks to Daytona to Railway and, even furth…
🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI
This episode has a fun personal twist: There’s a counterfactual world where I was employee #1 at Genesis Molecular AI, the company behind today’s episode. A cer…
Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks
We’re excited to have Databricks join us at AIEWF, among hundreds of the top companies in the AI Engineer ecosystem. LS subscribers can use their discount to ge…
Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan
AI Engineer World’s Fair regular bird tix will sell out ~today! Join us next week ahead of the Late Bird price hike and get >$40,000 in sponsor credits for atte…
The Professor of Outputmaxxing — Anjney Midha, AMP
Last 4 days before regular tickets sell out at AI Engineer World’s Fair - this is the single biggest gathering of AI Engineers, Founders, Leaders, and Researche…
🔬 The Self-Driving Lab — Joseph Krause, Radical AI
On the Science pod, we’ve been covering a lot of the ground on how AI is revolutionizing STEM, but one of our favorite off the record topics since our launch is…
Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs
The new AIEWF website is live! Get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free AIE WF tick…
🔬Scaling Past Informal AI - Carina Hong, Axiom Math
In 2025, seven-month-old startup Axiom solved all 12 of the problems Putnam exam (scoring 8/12 in the time limit) a prestigious undergraduate math exam. The 12/…
⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build
We’ve informally heard that Satya is a listener to LS for a couple years now, but it was still absolutely surreal to meet him and do a live pod at Build, togeth…
GitHub's plan for Agents — Kyle Daigle, GitHub
I’m excited to work with Microsoft once again as the presenting sponsors of the AI Engineer World’s Fair! We’ll streaming live from MS Build today for a special…
Why Video Agent models are next — Ethan He, xAI Grok Imagine
We’re announcing AIEWF speakers this week! Take the AI Engineering Survey!Today’s guest Ethan first joined us for the LS Paper Club as the lead on NVIDIA Cosmos…
The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray
The new AIEWF website is live! CFPs close in 2 days and we will run our first New Engineer Orientation this weekend, get your tickets booked ASAP as they -will-…
🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
Editor’s note: In our first BioHub pod with Priscilla and Mark they discussed their acquisition of EvoScale, led by Alex Rives, who is now Head of Science at Bi…
Giving Agents Computers — Ivan Burazin, Daytona
Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets!On the product side, everyone is getting Computer - Perplexity, Manus, Cursor, an…
Railway: The Agent-Native Cloud — Jake Cooper
Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets!This was recorded before Railway suffered a major GCP outage on May 19, despite b…
The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
The future of war has been evolving before our eyes in Ukraine, yet the west still plans to fight the last war. In this special episode, guest host Noah Smith (…
AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge
Special discounts up for AIE Melbourne (LS discount) and AIE World’s Fair (group discounts up to 25% - CFPs still open for Autoresearch and Vertical AI) Cya the…
🔬Doing Vibe Physics — Alex Lupsasca, OpenAI
Some people are going crazy over GPT 5.5. Some people. This is the story of the Jagged Frontier. People who use AI to write emails or even code implementation w…