Latent Space: The AI Engineer Podcast
Episodes 235 total
Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition
From building Applied Intuition from YC-era autonomy tooling into a $15B physical AI company, Qasar Younis and Peter Ludwig have spent the last decade living th…
AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)
Today, we check in a year after the first Unsupervised Learning x Latent Space Crossover special to discuss everything that has changed (there is a lot) in the…
Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO
Early bird discounts for the San Francisco World’s Fair, the biggest AIE gathering of the year, end today - prices will go up by ~$500 tonight so do please lock…
🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik
Today, we explain this piece of “clickbait” from our guest!TL;DR: 95% of cancer treatments fail to pass clinical trials, but it may be a matching problem — if w…
Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion
For all those who missed out on London, see you in Miami next week!Notion, the knowledge work decacorn, has been building AI tooling since before ChatGPT, with…
Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony
We’re proud to release this ahead of Ryan’s keynote at AIE Europe. Hit the bell, get notified when it is live! Attendees: come prepped for Ryan’s AMA with Vibhu…
Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"
Fresh off raising a monster $15B, Marc Andreessen has lived through multiple computing platform shifts firsthand, from Mosaic and Netscape to cofounding A16z. I…
Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun
We’ve been on a bit of a mini World Models series over the last quarter: from introducing the topic with Yi Tay, to exploring Marble with World Labs’ Fei-Fei Li…
Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample
Mistral has been on an absolute tear - with frequent successful model launches it is easy to forget that they raised the largest European AI round in history la…
🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik
Materials science is the unsung hero of the science world. Behind every physical product you interact was decades of research into getting the properties of mat…
Dreamer: the Personal Agent OS — David Singleton
Mar 23 update for Latent Spacenauts: this episode was recorded before the Dreamer team announced they were joining Meta Superintelligence Labs, and it turned ou…
Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop
Claude Cowork came out of an accident.Felix and the Anthropic team noticed something interesting with Claude Code: many users were using it primarily for all ki…
Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer
Turbopuffer came out of a reading app.In 2022, Simon was helping his friends at Readwise scale their infra for a highly requested feature: article recommendatio…
NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)
Join Kyle, Nader, Vibhu, and swyx live at NVIDIA GTC next week!Now that AIE Europe tix are ~sold out, our attention turns to Miami and World’s Fair!The definiti…
Cursor's Third Era: Cloud Agents
All speakers are announced at AIE EU, schedule coming soon. Join us there or in Miami with the renowned organizers of React Miami! Singapore CFP also open!We’ve…
Every Agent Needs a Box — Aaron Levie, Box
The reception to our recent post on Code Reviews has been strong. Catch up!Amid a maelstrom of discussion on whether or not AI is killing SaaS, one of the top p…
METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity
This is a free preview of a paid episode. To hear more, visit www.latent.spaceAIE Europe CFP and AIE World’s Fair paper submissions for CAIS peer review are due…
[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka
Swyx joined SAIL! Thank you SAIL Media, Prof. Tom Yeh, 8Lee, Hamid Bagheri, c9n, and many others for tuning into SAIL Live #6 with Nathan Lambert and Sebastian…
🔬Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI
Editor’s note: CuspAI raised a $100m Series A in September and is rumored to have reached a unicorn valuation. They have all-star advisors from Geoff Hinton to…
Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis
This is a free preview of a paid episode. To hear more, visit www.latent.spaceFirst speakers for AIE Europe and AIEi Miami have been announced. If you’re in Asi…